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Amlodipine-Atorvastatin combination is administered to patients for dose convenience. Caduet consists of two ingredients with different actions. Amlodipine reduces blood pressure and thus reduces the incidence of stroke and heart attack. Amlodipine is a dihydropyridine calcium channel blocker. Amlodipine has slow oral absorption and hence does not show early vasodilator side effects of calcium channel blockers. The oral bioavailability of Amlodipine is high and it is very long acting. Atorvastatin inhibits 3-Hydroxy -3-methyl glutaryl coenzyme A (HMG CoA) to mevalonate. This is the rate-limiting step in cholesterol biosynthesis. You can buy Caduet online from our pharmacy.

Manufacturer: Nicholas-Pirama	Average Delivery Time: 12-21 Business Days
Brand Name: Caduet	Tell a Friend

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How does Amlodipine -Atorvastatin / Generic Caduet work?
Amlodipine acts mainly by arteriolar dilatation and reflex sympathetic stimulation of heart that causes a fall in blood pressure. Amlodipine inhibits transmembrane influx of calcium ions to vascular smooth muscles and cardiac muscle. Atorvastatin competitively inhibits HMG CoA to mevolonate by enzyme HMG CoA reductase and lowers the blood cholesterol levels. Atorvastatin increases the expression of hepatic LDL receptors to enhance the uptake and metabolism of cholesterol. The combined action of the ingredients helps Caduet in effectively reducing the blood pressure.

Side effects of Caduet
The common side effects reported with Caduet are arrhythmia, bradycardia, chest pain, hypotension, syncope, postural hypotension, peripheral neuropathy, tremor, vertigo, anorexia, constipation, dyspepsia, dysphagia, flatulence, vomiting, allergic reaction, sexual dysfunction, dry mouth and increases sweating.

Guidelines before using Amlodipine-Atorvastatin
Caduet should be administered with caution in patients with aortic stenosis. Caduet is not recommended in pregnancy and during lactation. Avoid activities that require alertness during the treatment with Amlodipine -Atorvastatin as it can cause dizziness. There are also incidences of myopathy or rhabdomyolysis with the use of Caduet. Amlodipine -Atorvastatin should not be administered in patients with active liver disease or a history of liver disease. Caduet is contraindicated with substantial quantities of alcohol. The bile acid resins and Amlodipine -Atorvastatin should not be administered together.

What are the common dosages of Generic Caduet?
The recommended starting dosage of Amlodipine is 5mg once daily. This dose can be titrated in 7 to 14 days to a maximum of 10mg once daily. In elderly patients and in patients with hepatic dysfunction the starting dose is 2.5mg once daily. The recommended dose for coronary artery disease is 5-10mg once daily. The starting dose of Amlodipine in pediatric patients (6-17years) is 2.5-5mg once daily. The recommended starting dosage of Atorvastatin is 10-20 mg/day administered at any time of the day. The dose range of Atorvastatin is 10-80mg daily. The titration of dose should be done in an interval of 4 weeks according to response of the patient. The dose of Atorvastatin in pediatric patients (10-17years of age) is 10mg/day. The maximum tolerated dose for pediatric patients is 20mg/day

Difference between Brand and Generic Amlodipine -Atorvastatin
The Brand and generic Caduet contains Amlodipine and Atorvastatin as active ingredients. The generic and brand forms acts in the same way. The difference between brand and generic forms are packaging, pricing and the brand name. You can buy cheap Caduet pills when it is sold as a generic variant.

Where and How to buy Amlodipine-Atorvastatin / Generic Caduet
You can purchase Caduet medicine online from our pharmacy. When you order Caduet drug online from us, it will reach your doorstep without any hassles. We guarantee the lowest prices when you buy Caduet online from us.

Why is the price of Amlodipine-Atorvastatin / Generic Caduet so cheap at Aclepsa.com?
At Aclepsa.com, we believe in providing the best drugs at the cheapest prices. To meet this objective, we are continuously working out methods to reduce the cost. Some of the initiatives taken are direct sourcing from manufacturer and bulk ordering. All cost savings accrued translate to cheaper prices of our drugs.