

Simvastatin is a prodrug and hydrolysed to simvastatin acid after administration. Zocor is given in adolescent patients (10-17 years of age) who have genetically induced cholesterol problem. Simvastatin is the most potent and best tolerated hypolipidemic drugs. Zocor inhibits 3-Hydroxy -3-methyl glutaryl coenzyme A (HMG CoA) to mevalonate. This is the rate-limiting step in cholesterol biosynthesis. Zocor is a statin, which is lipophilic in nature. Simvastatin is given orally in precursor lactone form. Zocor undergoes extensive first pass metabolism. Simvastatin reduces the risk of mortality, myocardial infarction and need for coronary and non-coronary revascularization procedures in patients with high risk of coronary events. Simvastatin can be administered along with bile acid sequestrants. You can buy Zocor online from our pharmacy effortlessly with just the click of a mouse.
| Manufacturer: Cipla | Average Delivery Time: 12-21 Business Days |
| Brand Name: Zocor | Tell a Friend |
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| Quantity | Price | Price Per Pill | ||
|---|---|---|---|---|
| 90 pills | $99.00 | $1.10 | ![]() |
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How does Simvastatin / Generic Zocor work?
Simvastatin competitively inhibits HMG CoA to mevolonate by enzyme HMG CoA reductase. This increases the expression of LDL receptors on liver cells and increased receptor mediated uptake and catabolism of cholesterol. Simvastatin decreases the level of VLDL and TG and increases the level of HDL-C.
Side effects of Zocor
The common side effects reported with Simvastatin are edema, swelling, abdominal pain, atrial fibrillation, constipation, gastritis, diabetes mellitus, myalgia, head ache, insomnia, vertigo, bronchitis, sinusitis and urinary tract infection.
Guidelines before using Simvastatin
You should start a standard cholesterol lowering diet before starting treatment with Zocor. The dose of Simvastatin should be adjusted in patients with severe renal impairment. There are incidences of myopathy or rhabdomyolysis when high doses of Simvastatin are taken along with cyclosporine or danzol. It is not advisable to consume the Zocor pills during pregnancy and lactation. Simvastatin is not recommended in pediatric patients below the age of 10. Zocor should not be administered in patients with active liver disease. Avoid taking alcohol during treatment with Zocor. The administration of Simvastatin in elderly patients should be done with caution as it can cause serious muscle damage.
What are the common dosages of Generic Zocor?
The recommended starting dosage of Simvastatin is 20-40mg/day given along with evening meals. The maximum dose of Zocor is 80mg given in single or two divided doses. The dose of Simvastatin in adolescent patients (10-17years of age) is 10mg once a day and the maximum recommended dose is 40mg/day. In patients with severe renal impairment, the starting dose is 5mg/day.
Difference between Brand and Generic Simvastatin
Brand and generic Zocor contains Simvastatin as the active ingredient. . The mechanism of action is same for both generic and brand forms. The difference between brand and generic forms are packaging, pricing and the brand name. The generic version is cheaper in cost as there are no expenditure on research and development. You can buy cheap Zocor pills when it is sold as a generic drug.
Where and How to buy Simvastatin / Generic Zocor?
You can purchase Zocor medicine online from our pharmacy. When you order Zocor drug online from us, it will reach your doorstep without any hassles. You can also be assured of the best quality drug when you buy Zocor online from our pharmacy.
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